Your digestive system is the main entry point of outside toxins, and as such is an important barrier between you and environmental toxins and invaders. It makes sense then that 80 percent of your immune system is in your gut. Your gut-associated lymphatic tissue (GALT) and microbiome are components of your immune system that are attached to the mucosal lining of your intestines. When that lining is covered with old, rotting feces, it makes it difficult for your immune system to do its job, and as a result, you catch colds and flus more easily, and the gut is virtually defenseless against invading parasites and Candida fungal overgrowth.
If you want to get more scientific, broccoli and similar vegetables contain a compound known as indole glucosinolates. The stomach digests the compound and converts it into indolocarbazole (ICZ). In turn, ICZ activates the stomach’s hydrocarbon receptors (AHR). The AHR resides in your intestines and regulates gut barrier function and removes environmental contaminants.
In truth, there are very few reported complaints about herbal laxatives when properly used. Problems occur when people dramatically overdose on such products, or more significantly, when manufacturers promote them for inappropriate uses.  For example, several years ago, there was an incident in which a healthy young woman in her 30's used a "dieter's tea" product (a senna based drink) to lose weight. She died for no apparent reason, and the doctor's said it must have been the senna in the tea.
Foods that cause colon blockages are acid-forming — particularly high-protein diets without enough fiber. This leads to general malaise in the body. The colon's tissue eventually becomes inflamed, reducing its ability to do its job, which is to allow only water, minerals and vitamins to pass into the bloodstream. If yeasts, molds, fungus, bacteria, parasites or fecal material enter the bloodstream and connected tissue, the body's pH will be thrown out of balance.

Dr. Jensen also described the problem associated with mucoid plaque (thickened intestinal mucus) as: "The heavy mucus coating in the colon thickens and becomes a host of putrefaction. The blood capillaries to the colon begin to pick up the toxins, poisons and noxious debris as it seeps through the bowel wall. All tissues and organs of the body are now taking on toxic substances. Here is the beginning of true autointoxication on a physiological level."
Nature’s Secret 15-Day Weight Loss Cleanse & Flush helps stimulate healthy digestion and supports cleansing of the digestive tract.* The botanicals and fiber in this product may help reduce bloating, clean out the digestive system and help to flatten the appearance of the abdomen.* Once your digestive system is cleansed, absorption of nutrients and energy from food is enhanced, making you feel lighter, more energized and healthier.*
The gut is the basis of our health – it’s the first line of defense against pathogens, it’s where we digest and absorb nutrients and where we house our gut microbes, also known as gut bacteria. Poor gut health is now thought to be strongly linked to a compromised immune system, malnutrition and poor mood regulation, and plays a role in arthritis and obesity, according to a recent review of scientific literature published in the journal BMC Medicine.
A person who does a cleanse may initially lose a few pounds, but that is a temporary loss, resulting from the removal of water weight and stool, and not from a permanent loss of fat. Although it could be motivating to see results on the scale for a few days, cleansing is not a long-term solution to a weight problem, Wolf said. [5 Experts Answer: Is There Such Thing as a Healthy Juice Cleanse?]
A colon cleanse makes your digestive system more effective, as when it is cleansed it begins to expel undigested waste from your system, clearing up the space so that nutrients can be more easily absorbed in the future. If waste stays in your body for too long, it can end up causing illness from breeding bacteria and a clean colon detox will allow undigested waste to easily pass through your system.
It also uses more neurotransmitters to digest and process this junk food, leading to an imbalance in your “feel good” hormones, if not a deficiency. When you are under stress, these hormones are signaled by the brain to “speed up” and this chemical surge causes everything from anxiety, insomnia, trouble swallowing, and the “butterflies” in your stomach, to diarrhea, cramping, and neurotransmitter deficiencies. Colon cleansing: a popular, but misunderstood natural therapy
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